With a poetic, exuberant visual language, she develops feminist counter-mythologies that subvert patriarchal narrative structures. A central work is her long-term project Dark Continent (DC: Productions), inspired by Christine de Pizan's The Book of the City of Ladies, in which she designs an allegorical “city of women.”

Her works have been shown internationally, including at The Cosmic House, Turner Contemporary, Tate, Serpentine Galleries, UK, Fondazione Sandretto Re Rebaudengo, Italy, Grazer Kunstverein, Austria, and Tensta Konsthall, Sweden. In 2019, she was awarded the Turner Prize alongside three other artists. In 2023, Shani was the subject of solo exhibitions at KM21, The Hague, and the Contemporary Arts Center in Cincinnati. Significant projects such as DC: Semiramis were presented at the Glasgow International Festival and The Tetley in Leeds. In 2025, she presented two highly acclaimed exhibitions, The Sun Is a Flame That Haunts The Night at the High Line in New York and The Spell or The Dream, a large-scale audiovisual installation at Somerset House in London.